主要学习与工作经历: 1.2020-09至今,永利yl23411no1齐鲁医学部本科教育办公室副主任 2.2021-09至今,永利yl23411no1,控制科学与工程学院,教授 3.2013-09至2014-09,美国加州大学戴维斯分校,医学院,访问学者 合作导师:Nipavan Chiamvimonvat 4.2010-12至2021-12,永利yl23411no1,控制科学与工程学院,副教授 5.2009-01至2010-01,英国strathclyde大学,医学院,访问学者 合作导师:M Helen Grant 6.2005-01至2010-12,永利yl23411no1,控制科学与工程学院,讲师
目前主持或参加的研究项目: 1.科技部,国家重点研发计划,2019YFE0117800,可吸入纳米污染物对眼睛及呼吸系统的毒性研究,215万,2020.12.01-2023.11.30,主持,在研。 2.国家自然科学基金,面上项目,基于LMD-ICPMS的金属氧化物纳米颗粒对眼睛炎症模式及组织重塑研究,60万,2022.01.01-2025.12.31,主持,在研。 3.山东省科技厅,山东省重大创新工程,2021CXGC010506,早期胃癌AI图像识别及监测系统研发,1100万,2021.01.01-2024.12.31,参与,在研。 4.山东省自然科学基金,面上项目,ZR2021MH208,基于多维空间组织光谱成像的宫颈癌早期筛查机理研究,10万,2021.01.01-2024.12.31,主持,在研。 5.山东省科技厅,山东省重大创新工程,2019JZZY020904,基于生物光谱扫描技术的非侵入式宫颈癌早期筛查设备研发与产业化,933万,2019.06-2021.12,已结题,主持。 6.科技部,高端外国专家引进计划,GX20200015001,有效抑制新型冠状病毒的环糊精可溶性ACE2雾化喷剂研究,35万,2020.03-2021.12,主持,已结题。 7.科技部,高端外国专家引进计划,G2021150001L,工程纳米颗粒对靶器官炎症模式及组织重塑研究,40万,主持,在研。 8.科技部,高端外国专家引进计划,G20190015044,空气污染对儿童神经系统及心肺发育的生物学影响研究,26万,2019.01-2019.12,已结题,主持。 9.一般横向项目,非小细胞肺癌脑寡转移多组学测试分析研究,30万,2019.05-2021.05,主持,已结题。 10.山东省科技厅,省重点研发计划,2018GSF118136(GG201709260070),基于机械式流转音传感器的远程肺功能智能服务云平台的研究,10万元,2018.04-2019.12,已结题,主持。 11.国家基金委,海外及港澳台学者合作研究基金项目,21728701,基于ES-HRAMS技术的大气粒子污染发生、演变、转运规律及毒性研究,19万元,2017.1-2019.12,已结题,主持。 12.永利yl23411no1,科研交叉项目,2017JC014,远程管理的可穿戴舌下神经刺激及膈神经起搏装置治疗睡眠呼吸暂停,2017/1-2019/12 ,35万元,已结题、主持。 13.中国博士后科学基金委,面上项目,2015M572044,miRNAs对心力衰竭过程中心脏重构调控作用研究,5万,2016.01-2018.12,已结题、主持。 14.国家自然科学基金委,青年项目,30900730,人新基因TINP1诱导增殖的机理和功能研究,20万元,2010.01-2012.12,已结题、主持。 15.山东省自然科学基金委,省自然科学基金联合基金,Y2008G06,基于粗集理论的虹膜识别关键技术研究,5万,2009.01-2011.12,已结题,参与。 16.山东省自然科学基金委,青年项目,Q2007D01,Id蛋白诱导胃癌转移潜能途径的研究,4.5万元,2008.01-2010.12,已结题、主持。
代表性论文: 1.Wei Li*, Xiangfeng Leng, Qiu Zhang, Cuifen Zhao4*, Chenguang Lv,Tengfei Xu.Nuclear localization signal of TGF-β-inducible nuclear protein 1 mediates functions of TINP1 in suppression of the p53 signaling pathway and promotion of cell proliferation,International Journal of Clinical and Experimental Medicine,2017,10(3):4748-4755 2.Xiaolin Sun, Haiying Weib, Dominique E. Youngd, Keith J. Beinc,Suzette M. Smiley-Jewellc, Qi Zhang, Ciara Catherine B. Fulgarc, Alejandro R. Castañedac,Alexa K. Phamc, Wei Li*&Kent E. Pinkerton.Comparison of time lag effects of wintertime california and china pm in healthy young mice,American Journal of Respiratory and Critical Care Medicine,2017,195:A3903,17.452 3.Wei Li., Liu, M., Zhao, C., Chen, C., Kong, Q., Cai, Z., & Li, D.MiR-1/133 attenuates cardiomyocyte apoptosis and electrical remodeling in mice with viral myocarditis,Cardiology Journal,2020,27(3):285-294 4.Wei Li*., Wei, H*. & Pinkerton, K. E*.In vivo and in vitro inflammatory responses to fine particulate matter (PM2.5) from China and California,Toxicology Letters, 2020,328:52-60 5.Chen Cai,Liu Xuejian,Wang Xianfeng,Qu Wenxiu,Wei Li*,Dong Leilei.Effect of air pollution on hospitalization for acute exacerbation of chronic obstructive pulmonary disease, stroke, and myocardial infarction,Environmental Science and Pollution Research, 2020,27(3):3384-3400 6.Zhang Jingjing, Fulgar Ciara C, Mar Tiffany, Young Dominique E, Zhang Qi, Bein Keith J, Cui Liangliang, Castaneda Alejandro, Vogel Christoph F. A, Sun Xiaolin, Wei Li.TH17-induced neutrophils enhance the pulmonary allergic response following balb/c exposure to house dust mite allergen and fine particulate matter from California and China,Toxicological Sciences,2018,164(2):627-643 7.Xiaolin Sun, Haiying Wei, Dominique E. Youngd, Keith J. Beinc, Suzette M. Smiley-Jewellc, Qi Zhang, Ciara Catherine B. Fulgarc, Alejandro R. Castañedac, Alexa K. Phamc, Wei Li*.Differential pulmonary effects of wintertime California and China particulate matter in healthy young mice,Toxicology Letters,2017,278:1-8 8.Wei Li, Chun-hua Zhang,Yi-lin Hong, JunLi, Yong-mei Hu, Cui-fen Zhao*Inhibitor of DNA-binding-1/inhibitor of differentiation-1 (ID-1) is implicated in various aspects of gastric cancer cell biology,Molecular Biology Reports 2012 ,39(3):3009-15 9.Wei Li , Cui-fen Zhao*, Yi-lin Hong, Jun Li,Chun-hua Zhang, Hui Xiong,Regulation of growth and sensitivity of gastric cancer cells to cisplatin by modulation of Inhibitor of DNA Binding or Differentiation Protein (ID) expression ,Laboratory Medicine,2012,43(5):189-196 10.Wei Li,Qing-yu Kong,Cui-fen Zhao*, Fang Zhao,Fu-hai Li,Xia Wang,Rong Wang, Yong-mei Hu,Hua Mu,Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells,Brazilian journal of medical and biological research, 2013 ,46(12):1047-1055 11.Urotensin II contributes to collagen synthesis and up-regulates Egr-1 expression in cultured pulmonary arterial smooth muscle cells through the ERK1/2 pathway[J]. Biochem Biophys Res Commun, 2015, 467(4):1076-1082 12.Chen Cai,Wang Xianfeng,Lv Chenguang,Wei Li*,Ma Dedong,Zhang Qi,Dong Leilei.The effect of air pollution on hospitalization of individuals with respiratory and cardiovascular diseases in Jinan,China,Cardiology Journal,2019,98(22):e15634 13.Ma Z, Zhou T, Wei Li*, and Ma D*.Impact of end-expiratory pressure fluctuation on tidal volume in the trilevel positive airway pressure mode,The Clinical Respiratory Journal, 2020,14(10): 980-990 14.Wei Li., Song, A.-P., Zhao, F., Hu, Y.-M., Hua, M. A novel human TINP1 gene promotes cell proliferation through inhibition of p53 and p21 expression. Oncology Reports, 2013, 30(4):1848-1852 15.Chenguang Lv, Xianfeng Wang, Na Pang, Lanzhong Wang, Yuping Wang, Tengfei Xu, Yu Zhang, Tianran Zhou & Wei Li*.The impact of airborne particulate matter on pediatric hospital admissions For pneumonia among Jinan children: a case-crossover study,Journal of the Air and Waste Management Association,2017,67(6),669-676 16.Wei Li*, Xiangfeng Leng, Qiu Zhang, Cuifen Zhao4*, Chenguang Lv,Tengfei Xu.Nuclear localization signal of TGF-β-inducible nuclear protein 1 mediates functions of TINP1 in suppression of the p53 signaling pathway and promotion of cell proliferation,International Journal of Clinical and Experimental Medicine,2017,10(3):4748-4755 17.Chen Cai,Liu Xuejian,Wang Xianfeng,Wei Li*,Qu Wenxiu,Dong Leilei,Li Xiyuan,Rui Zhiqing,Yang Xueqing.Risk of temperature, humidity and concentrations of air pollutants on the hospitalization of AECOPD,PLoS ONE,2019,14(11):e0225307 18.Yu Zhang, Wei Li*.Batch preparation of LKB1 condition gene knockout mice based on PCR ,Proceedings - 2017 Chinese Automation Congress,2017,1337-1339,Accession number: 20183005598851 19.Yuping Wang, Wei Li*.Construction of rat vascular smooth muscle cell calcification model and VD3-induced vascular calcification in mice,Proceedings - 2017 Chinese Automation Congress, CAC 2017,1333-1336,Accession number: 20183005597955 20.Meng X, Wei Li, Kong X, Ma Z, Chi H.Scarf Defect Detection Method Based on Periodicity of Braided Texture,Journal of Physics: Conference Series,2020,1631(1):12066,Accession number: 20204209356916 21.Chen C, Li X, Meng X, Ma Z, Wei Li*, Ma D.The Effect of Air pollution on the Hospitalization for AECOPD,IOP Conference Series: Earth and Environmental Science,2020,450(1),12092,Accession number: 20201608458834 22.Leilei Dong,Wei Li,Dedong Ma,Chenguang Lv,Cai Chen. The evaluation and comparison on different types of resident doctors in training through DxR Clinician system,Journal of Physics: Conference Series,2020,1549(4):42076,Accession number: 20202908944582 23.Li, Xiyuan; Chen, Cai ; Li, Wei ; Ma, Dedong,Relationship between Particulate Matter Exposure and Inhaled Amount for Different Exercise Patterns of Healthy Adults,IOP Conference Series: Earth and Environmental Science,2020,450(1):12091,Accession number: 20201608458833 24.Cai Chen,Wei Li,Leilei Dong,Xiyuan Li. The Effect of Meteorological Factors, Seasonal Factors and Air Pollutions on the Formation of Particulate Matter,IOP Conference Series: Earth and Environmental Science,2020,450(1),12012,Accession number: 20201608458854 25.Cai Chen, Wei Li*, Dedong Ma. Sleep breathing data analysis based on econometrics,2019 6th International Conference on Systems and Informatics, ICSAI 2019,5:2352-5398,Accession number: 20201208328959 26.Ma Z, Wei Li*. Design of Sublingual Nerve Electrical Stimulation Module for Sleep Respiratory Mask[C]//2019 12th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI). IEEE, 2019: 1-5,Accession number: 20200708158424 27.Wei Li., Xiong, H., Hong, Y.-L., Zhang, C.-H., Liu, C.-C. Prostate specific antigen promoter-driven adenovirus-mediated expression of both ODC and AdoMetDC antisenses inhibit prostate cancer growth. Chinese Journal of Cancer Research, 2010, 22(3):224-230
近三年已获授权发明专利: 1.DEVICE AND METHOD MONITORING HUMAN BREATHING STATE BASED ON IMAGE, 卢森堡专利, 2020 2.LASER GUIDED POSITIONING DEVICE AND METHOD FOR AUTOMATIC TUMOR PUNCTURE MACHINE, 卢森堡专利, 2020 3.IMAGE FILTERING INTENSITY ENHANCEMENT APPARATUS FOR BIOLOGICAL SPECTRUM SCANNING TECHNOLOGY, 卢森堡专利, 2020 4.METHOD AND SYSTEM FOR RECOGNIZING HUMAN POSTURE ON ELECTRIC BED,PCPIP202007NL,荷兰专利,2022 5.DATA PROCESSING SYSTEM FOR ACQUIRING TUMOR POSITION AND CONTOUR IN CT IMAGE AND ELECTRONIC EQUIPMENT,PCPIP202008NL,荷兰专利,2022 6.PRECISE POSITIONING SYSTEM FOR THREE-DIMENSIONAL POSITION OF TUMOR BY MULTI-IMAGE FUSION,PCPIP202009NL,荷兰专利,2022 7.基于激光定位的标定水箱摆位方法及系统,发明,2020104312008,2020-05-20,永利yl23411no1,李玮,孟祥伟,袁双虎,雷晟暄,马志祥 8.一种加速器剂量的动态测量方法,发明,2020103446965,2020-04-27,永利yl23411no1,李玮,陈财,袁双虎,雷晟暄,马志祥,孟祥伟 9.一种生物光子宫颈癌筛查仪,发明,2019108767527,2019-09-17,山东省肿瘤防治研究院(山东省肿瘤医院),永利yl23411no1,袁双虎,李玮,李潇箫,刘宁,魏玉春,李莉,王勇,赵伟,刘聿辉,于金明 10.一种引导式人工口咽通道吸痰装置及工作方法,发明,2021108462121,2021-07-26,永利yl23411no1,周生余,秦念博,孙海航,张发艳,李玮 11.一种实现全方位测量的激光粒度仪及测量方法,发明,2020110917722,2020-10-13,永利yl23411no1,李玮,孙海航,范立嵩,雷晟暄,韩毅,王平 12.一种凝溶胶蛋白包结及纳米化方法及混悬液,发明,2020105042650,2020-06-05,永利yl23411no1,李玮,范立嵩,郄淑燕,杭伟,袁双虎,雷晟暄,马志祥,孟祥伟,孙海航 13.耳朵外观轮廓三维扫描系统及方法,发明,2020105806109,2020-06-23,永利yl23411no1,李玮,薛峰,赵宇航,雷晟暄,安纲,马志祥,孟祥伟,张婉钰,孟真,孔祥虹,燕群,谢龙悦 14.一种全耳再造术耳部支撑架的3D打印方法及系统,发明,2020104020902,2020-05-13,永利yl23411no1,李玮,薛峰,孙海航,安纲,雷晟暄,孟芮帆,马志祥,孟真,孔祥虹 15.医用直线加速器使用环境实时监控方法及系统,发明,2020104399478,2020-05-22,永利yl23411no1,李玮,孟祥伟,袁双虎,雷晟暄,马志祥,孙海航,赵宇航 16.用于核磁共振与放疗相融合的磁场制备结构、设备及系统,发明,2020104028035,2020-05-13,山东省肿瘤防治研究院(山东省肿瘤医院),永利yl23411no1,袁双虎,李玮,王碧瑶,韩毅,李莉,刘宁,祝守慧,于金明 17.一种标定水箱的光学与金属复合定位方法及系统,发明,202010431380X,2020-05-20,永利yl23411no1,李玮,孟祥伟,袁双虎,雷晟暄,马志祥 18.一种气溶胶颗粒的检测系统及方法,发明,2020102438321,2020-03-31,永利yl23411no1,李玮,范立嵩,韩毅,王平,袁双虎,孟祥伟,马志祥,孙铁锋 19.基于粒子加速器的核磁共振磁场测量方法及系统,发明,2020103987519,2020-05-12,山东省肿瘤防治研究院(山东省肿瘤医院),永利yl23411no1,济南比山网络科技有限公司,袁双虎,李玮,方永祥,李莉,刘宁,吕慧颖,于金明 20.基于磁共振影像的肿瘤位置标定系统及设备,发明,2020101965479,2020-03-19,永利yl23411no1,李玮,袁双虎,韩毅,张婉钰,马志祥,孟祥伟 21.一种可防止拨片变形的定位机构及呼吸功能检测仪,发明,2020102859871,2020-04-13,永利yl23411no1,李玮,雷晟暄,马德东,马志祥,孟祥伟 22.一种无创呼吸机的呼气末CO<sub>2</sub>监测装置及方法,发明,2020101610147,2020-03-10,永利yl23411no1,李玮,季心宇,马德东,韩毅,马志祥,孟祥伟 23.一种无创呼吸机数据安全传输方法及系统,发明,2020106016884,2020-06-28,永利yl23411no1,李玮,马德东,季心宇,雷晟暄,马志祥,孟祥伟,孙海航,赵宇航,宋爱萍,燕群 24.防尘式宫颈筛查仪用触屏控制面板及防尘式宫颈筛查仪,发明,2019109547473,2019-10-09,永利yl23411no1,李玮,袁双虎,韩毅,孟祥伟,马志祥 25.一种宫颈穿刺活检钳及其使用方法,发明,2019109555253,2019-10-09,永利yl23411no1,李玮,袁双虎,韩毅,孟祥伟,马志祥 26.一种基于VR眼镜的肿瘤穿刺实时模拟系统,发明,2019108716525,2019-09-16,山东省肿瘤防治研究院(山东省肿瘤医院),永利yl23411no1,袁双虎,李玮,孟祥伟,李莉,刘宁,王素贞,于清溪,赵芬 27.一种材料数据收集装置及其工作方法,发明,2019108762237,2019-09-17,山东省肿瘤防治研究院(山东省肿瘤医院),永利yl23411no1,袁双虎,李玮,刘宁,杨奉常,刘治国,魏玉春,李莉,李潇箫,周士振,于金明 28.肿瘤穿刺中根据人体姿态确定穿刺路径的系统,发明,2019112601717,2019-12-10,永利yl23411no1,李玮,刘丽昕,袁双虎,韩毅,马志祥,孟祥伟,宋涵 29.一种肿瘤自动穿刺机的激光引导定位装置,发明,2019109488403,2019-10-08,永利yl23411no1,李玮,孟祥伟,袁双虎,韩毅,马志祥,许浩然,刘凯华,冯少飞 30.一种自动巡航电动病床的自主避障与路径规划方法和系统,发明,2019110536605,2019-10-31,永利yl23411no1,李玮,马志祥,韩毅,袁双虎,孟祥伟 31.一种用于肿瘤穿刺的穿刺辅助装置及工作方法,发明,2019108569009,2019-09-09,永利yl23411no1,李玮,宋涵,袁双虎,韩毅,马志祥,孟祥伟,许浩然,刘凯华,冯少飞 32.一种电动病床的室内自适应巡航控制系统及方法,发明,2020100057096,2020-01-03,永利yl23411no1,李玮,董蕾蕾,韩毅,袁双虎,马志祥,孟祥伟 33.一种双电机驱动的可移动病床及其工作方法,发明,2019111488702,2019-11-21,永利yl23411no1,李玮,李希元,韩毅,袁双虎,马志祥,孟祥伟 34.一种病床的原地转弯控制系统及控制方法,发明,2019107295529,2019-08-08,永利yl23411no1,李玮,马志祥,韩毅,王建波,程玉峰 35.获取CT图像中肿瘤位置和轮廓的数据处理系统及电子设备,发明,2019108820162,2019-09-18,山东省肿瘤防治研究院(山东省肿瘤医院),永利yl23411no1,袁双虎,李玮,孟祥伟,于清溪,刘宁,魏玉春,李莉,李潇箫,刘长民,于金明 36.一种自动巡航电动病床与电梯交互方法及系统,发明,2019110566511,2019-10-31,永利yl23411no1,李玮,陈财,韩毅,袁双虎,孟祥伟,马志祥 37.一种用于机械臂穿刺的活检针及穿刺装置,发明,2019105962227,2019-07-03,永利yl23411no1,李玮,韩毅,王建波,马志祥,孟祥伟,陈财,范圣龙,陈霄,孙铭泽,许怡晴 38.一种适用于放疗科的可移动床,发明,2019102753179,2019-04-08,永利yl23411no1,李玮,王建波,程玉峰,周天苒 39.一种斑马导丝及引导装置,发明,2019102502293,2019-03-29,永利yl23411no1,李玮,王彭,吕家驹,蒋绍博,屈明明,姜宏如,刘茜娜,刘孟君,王嘉睿 40.一种基于太阳能的新型家居控制系统,实用新型,2018207401266,2018-05-17,永利yl23411no1,陈财,李玮,雷晟暄,汪静,任冲 41.一种制取玫瑰花萃取原液染布料的方法,发明,2017112617364,2017-12-04,永利yl23411no1,李玮,路遇,陈锐,董蕾蕾,张宇,王玉萍,陈财 42.一种血栓切除系统,实用新型,2017203806076,2017-04-12,永利yl23411no1,山东省千佛山医院,李玮,秦士勇,张宇,王玉萍,马志祥,曹际新,蔡令一,徐兆杰 43.一种血栓切除系统、制备方法及工作方法,发明,2017102422656,2017-04-12,永利yl23411no1,山东省千佛山医院,李玮,秦士勇,张宇,王玉萍,马志祥,曹际新,蔡令一,徐兆杰 44.基于机器视觉检测平台的液体药瓶异物检测方法,发明,2015102426465,2015-05-13,永利yl23411no1,李玮,雷鸣,廖大鹏,刘军,李俊恩,张辉,刘传良,王江涛,王宏亮,赵翠芬,赵运德,谭径元 45.一种基于图像处理的药瓶液位检测方法,发明,2015102425922,2015-05-13,永利yl23411no1,李玮,韩毅,赵翠芬,赵运德,孙晓琳,吕晨光,蒋润辉,许腾飞,曾海滨,谭径元 46.一种男性内置隐藏式导尿管,实用新型,201920258681X,2019-02-28,永利yl23411no1,李玮,王彭,吕家驹,蒋绍博,屈明明,吴文霞,蒋望舒,吕佳慧,郑梦璇 47.弓型臂螺旋加压式复位钳,实用新型,2016214776493,2016-12-30,永利yl23411no1,山东中医药大学附属医院,山东省日照第一中学,李玮,张鹏,郭珂君,陈财,董蕾蕾,袁月 主编教材: 系统生理学,李玮,永利yl23411no1出版社,ISBN 978-7-5607-7026-0,出版时间:2021.05 细胞生物信息学,李玮,永利yl23411no1出版社,ISBN 978-7-5607-7237-0,出版时间:2021.11 系统生理学,李玮,人民军医出版社(北京),全国高等医学院校规划教材,ISBN 978-7-5091-1363-9,出版时间:2007.11 主讲课程: 本科专业基础课《生理学》、《人体解剖学》; 研究生专业通识课《心肺功能监测与支持设备》、《现代生物信息及技术概论》、《生物医学工程探索》(国际化课程); 线上课程《系统生理工程学》、《Physiological System Engineering》和《Human System Architecture》。 其中,《生理学》的课程近五年学时数达到288学时,《人体解剖学》的课程近五年学时数达到246学时。MOOC平台上的《系统生理工程学》结课3期,正在授课1期,总选课人数为17224人。 主持教改项目: 1.教育部产学合作协同育人项目,具有交互式观感的智慧雨课堂学习课件建设,省部级,2021年3月-2022年3月,主持人。 2.永利yl23411no1教育教学改革研究项目,基于虚拟仿真技术的体验式生理学习环境及任务模块教学,校级,2020年1月-2022年12月,主持人。 3.永利yl23411no1研究生教育教学改革研究项目,项目驱动的复合型学研一体化课堂建设,校级,2021年4月-2023年4月,主持人 4.系统生理学(国际化课程建设),本科生,2020-2022,校级,主持人; 5.人体解剖学(国际化课程建设),本科生,2020-2022,校级,主持人; 6.研究生国际化课程-生物医学工程探索,研究生,2020-2021,校级,主持人; 7.研究生国际化课程-现代生物信息与技术概论,研究生,2020-2021,校级,主持人; 8.生理学在线精品课程建设,本科生,2018-2020,校级,主持人; |